Cancer

Biomarker study

Significance

Reference

OA

Loss of chromosome 1p and 19q

Sensitive to chemotherapy and better prognosis

[21] [22]

NSCLC

ERCC1/MDR1 SNP DNA mehtylation and repair Kappa B Deletion of chromosome 11p15

Associated with sensitivity to platinum Predict chemosensitivity Predict chemosensitivity Resistance to gemcitabine

[23]

[24] -[26]

[27]

[27]

Brest

HER-2 BRCA 1 mutation P53 mutation TNBC

Poorer prognosis Conflict results of chemosensitivity Drug resistance Sensitive to chemotherapy and biological therapy

[28]

[29]

[29]

[30]

Stomach

Oncogene, antioncogenes, DNA repair, receptors,

Diagnosis and predict chemosensitivity

[31] [32]

Skin

DNA microarray

Diagnosis and predict chemosensitivity

[33]

PETs

Loss of heterogosity, alterations of oncogenesantioncogenes, growth factors and receptors

Prognostic significance Targetable gene and protein

[34]

Head and neck

EGFR P53 gene and protein

Prognosis Predict clinical outcome

[35]

AML

Microarray combine with flow cytometry

Predict chemosensitivity, diagnostic and pharmacokinetic study

[36]

OVA

CA-125 change

Predict the treatment outcome

[37]

OA TNBC PETs

Oligodendroglioma Triple negative breast cancer Pancreactic endocrine tumors